Popular dietary supplement linked to cancer risk, brain metastasis

The researchers used this technology to compare and examine how much NR levels were present in cancer cells, T cells and healthy tissues. Photo: Pexels

(Emily Henderson/ News Medical Net) –– While previous studies have linked commercial dietary supplements like nicotinamide riboside (NR), a form of vitamin B3, to benefits related to cardiovascular, metabolic and neurological health, new research from the University of Missouri has found NR could actually increase the risk of serious disease, including developing cancer.

The international team of researchers led by Elena Goun, an associate professor of chemistry at MU, discovered high levels of NR could not only increase someone’s risk of developing triple-negative breast cancer, but also could cause the cancer to metastasize or spread to the brain.

Once the cancer reaches the brain, the results are deadly because no viable treatment options exist at this time, said Goun, who is the corresponding author on the study. (…)

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