Services / Gynecology Center / Hysterosonography

Hysterosonography: What It Is, Benefits, and Risks

What is Hysterosonography?

Hysterosonography, also called sonohysterography or saline infusion sonography (SIS), is a specialized ultrasound procedure used to get a detailed look inside the uterus. It involves placing a small amount of sterile saline into the uterine cavity during a transvaginal ultrasound. The saline gently expands the cavity, allowing the provider to clearly see the uterine lining, shape, and any abnormalities that may be present.

Unlike X‑rays or CT scans, hysterosonography does not use radiation. It relies only on sound waves and is considered a safe, minimally invasive imaging method.

This procedure is typically performed in a clinic or imaging center and usually takes 15–30 minutes.

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Why is Hysterosonography Done?

Hysterosonography helps evaluate many gynecologic conditions, especially when a standard ultrasound doesn’t provide enough information.

Common Reasons for the Test

  • Abnormal uterine bleeding, including heavy periods, bleeding between cycles, or postmenopausal bleeding
  • Infertility evaluation, including repeated miscarriages, suspected uterine abnormalities, or pre‑IVF cavity assessment
  • Detection of growths such as fibroids, polyps, or scar tissue (adhesions) inside the uterine cavity
  • Clarifying unclear findings from a baseline transvaginal ultrasound when more detail is needed
  • Evaluating congenital uterine shape issues, such as a uterine septum

Additional Uses

Some hysterosonography exams also help assess:

  • Whether the fallopian tubes may be open
  • Presence of ovarian cysts
  • Antral follicle count (egg supply) in fertility evaluations

What to Expect During the Procedure

Step‑by‑Step Overview

  1. Positioning: You lie on the exam table with feet supported, similar to a pelvic exam.
  2. Transvaginal ultrasound setup: A slim ultrasound wand, covered with a sheath and gel, is inserted into the vagina.
  3. Catheter placement: A thin catheter is passed through the cervix into the uterus. This may cause brief cramping or pressure.
  4. Saline infusion: Sterile saline (about 10–15 mL) is slowly infused into the uterine cavity, gently expanding it. A tiny balloon on the catheter may help keep fluid inside.
  5. Imaging: As the cavity expands, the ultrasound provides high‑detail, real‑time images of the uterine lining and cavity. Your clinician evaluates the structure and any abnormalities.

Duration & Comfort

  • The exam typically takes 15–30 minutes.
  • Mild cramping is common during the infusion but usually passes quickly.
  • Because the procedure uses saline—not contrast dye—there is no allergy risk to imaging agents.
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Benefits of Hysterosonography

1. Exceptional Visualization of the Uterine Cavity

Saline infusion separates the uterine walls, making polyps, fibroids, scarring, and cavity abnormalities much easier to detect than on standard ultrasound.

2. Highly Accurate

Studies show diagnostic accuracy as high as 90–99% for common cavity abnormalities such as fibroids, polyps, and abnormal thickening.

3. Safe and Minimally Invasive

The procedure uses only ultrasound and sterile saline—no radiation, incisions, or anesthesia required.

4. Better Than Other Imaging Methods for Specific Problems

Hysterosonography often outperforms:

  • Standard ultrasound (limited cavity detail)
  • Hysterosalpingography (uses radiation)
  • MRI (less cavity-specific clarity)
  • Hysteroscopy (more invasive and requires anesthesia)

6. Valuable for Fertility Planning

Helps identify issues that could affect conception, implantation, and miscarriage risk. Often used prior to IVF.

Risks & Possible Side Effects

Hysterosonography is considered very safe, but mild side effects can occur.

Common Temporary Effects

  • Mild cramping during or after the procedure
  • Light spotting or watery discharge from the saline

Rare Risks

  • Pelvic infection, occurring in fewer than 1% of cases. Risk is higher in individuals with untreated tube blockage or infection.

When the Procedure Should Be Avoided

  • Suspected or confirmed pregnancy
  • Active pelvic inflammatory disease (PID) or pelvic infection
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Preparation & Aftercare

How to Prepare

  • The best time for the exam is just after your period but before ovulation (usually days 6–11). This ensures the lining is thin and easy to evaluate.
  • If bleeding heavily, your provider may adjust the timing.
  • You may be asked to take ibuprofen or acetaminophen one hour before the procedure to reduce cramping.
  • Empty your bladder right before the procedure.
  • A recent negative gonorrhea/chlamydia result (1 year if no new partner)

After the Procedure

  • Expect mild cramping or discharge for a few hours.
  • Most people return to normal activities immediately.
  • Call your clinician if you develop:
    • Fever
    • Increasing pelvic pain
    • Foul‑smelling discharge

Hysterosonography is a safe, minimally invasive, highly accurate imaging test used to evaluate the uterine cavity, especially when symptoms or baseline ultrasound results suggest an abnormality. By using saline to expand the uterus, this method provides superior visualization of polyps, fibroids, scarring, and cavity shape—information essential for diagnosing abnormal bleeding, infertility, or recurrent pregnancy loss. Most patients tolerate the procedure well, and complications are rare.

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