Breakthrough that wipes out ovarian cancer cells unveiled

(Jim Leffman/ The London Economic) — A cancer research breakthrough that wipes out ovarian cancer cells has been unveiled.

The cancer kills 11 British women every day with survival rates of only 35 per cent, according to Cancer Research UK. But researchers have developed what they call “one-two punch” that works by forcing cancer cells into a dying state called senescence before wiping them out using a process called senolysis.

They found drugs that blocked enzymes behind repairing DNA damage in cancer cells stopped the body becoming resistant to chemotherapy treatment. The study, published in the journal Nature Communications, shows the effectiveness of the “one-two punch” on cells of ovarian cancer patients.

Study co-author Francis Rodier, a researcher at the Centre hospitalier de l’Université de Montréal (CHUM) and the Université de Montréal, said: “In the case of epithelial ovarian cancer (EOC) – the most common and lethal ovarian cancer – we act in two stages.” (…)

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