1,000s of Canadian breast cancer patients will reap reward of no-chemo study: experts

(Sheryl Ubelacker/ Canadian Press) — When Lisa Freedman was diagnosed with breast cancer, a genetic test of her tumour suggested chemotherapy would have no effect on the risk of recurrence, allowing her to safely skip the treatment and its dreaded side-effects.

“When the test came back, it showed that I would have a 13 per cent chance of recurrence if I had chemo and a 12 per cent chance if I didn’t have chemo,” said the Toronto lawyer, 61.

“So that became an easy no-chemo decision,” said Freedman, who has been cancer-free for two years.

A recently published U.S.-led study of more than 10,000 women whose tumours were tested determined that most patients with early-stage estrogen-positive breast cancer and no lymph-node spread should be able to avoid chemo and be treated with surgery, radiation and a hormone-blocking drug like tamoxifen alone.

The study is the largest ever performed looking at breast cancer treatment, and its results are expected to spare thousands of women in Canada each year from having to undergo rounds of chemotherapy and its harsh side-effects. (…)

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